STUDY OF THE METHOD OF CLEANING OF TECHNOLOGICAL EQUIPMENT OF PHARMACEUTICAL AND CHEMICAL MANUFACTURES USING A MICELLAR DEZAKTIVATION SYSTEM

Abstract

Research of the method of purification of technological equipment of pharmaceutical and chemical industries using a new micellar system of decontamination based on a solid hydrogen peroxide source. Methodology. Dimethoate is chosen as the model substance of a characteristic chemical structure. As a model system for determining the efficiency of the decontamination system, the process of cleaning technological equipment for the production of herbicide on the basis of dimethoate was used. To determine the concentration of dimethoate in solutions, a validated HPLC technique was used. It  has  been  established  that  a  new  micellar  decontamination  system  based  on  a  solid hydrogen peroxide source is suitable for purification of process equipment in the model production process using  the  active  ingredient  of  dimethoate.  It  has  been  shown  that  the  decontamination  time  of  an contaminated solution with a content of dimethoate of 3000 ppm to a level below the quantitative limit is 120 minutes.  Originality. For the first time, the effectiveness of a new micellar system of decontamination on the
basis of a solid hydrogen peroxide source for the purification of process equipment in the modeling process for the production of pesticides based on dimethoate has been investigated.  
Practical  value.  Based  on  the  evaluation  of  the  efficiency  of  a  new  micellar  system  of decontamination  on  the  basis  of  a  solid  hydrogen  peroxide  source  in  the  process  of  decontaminating washable waters containing dimethoate, technological schemes for the purification of process equipment in
the chemical and pharmaceutical industries can be developed.